Hepatitis E

Written by Ashish Chandra Shrestha

Hepatitis E virus (HEV), also referred to as enterically transmitted non-A non-B hepatitis virus, has been associated with waterborne outbreaks since 1955. Availability of serological tests for hepatitis A and hepatitis B virus, identified this virus as a different causative agent of acute hepatitis. HEV is endemic in developing countries and associated with poor sanitation and water borne outbreaks. However, in developed countries, traditionally HEV was associated with travelers returning from HEV endemic countries. Zoonotic or food borne transmission has contributed to increase in number of locally acquired cases in developed nations. The epidemiology, pathogenicity and mode of transmission varies with infecting genotype of this virus.

Clinical Features



Cellular Characteristics




Additional Resources


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